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FEIGONG INSTRUMENTS (SHANGHAI) CO., LTD. · FGi-lab

Intelligent Nanoparticle Synthesis,
from High-Throughput Screening to Pilot Scale-Up

Microfluidic precision-mixing platforms for nanomedicine preparation — from 60 μL ultramicro-volume screening up to 500 mL/min pilot production, accelerating the development and industrialization of mRNA vaccines, LNPs, liposomes and polymeric nanoparticles.

Explore Products Get a Quote
NP-HT.S High-Throughput Nanoparticle Synthesis System
30–200 nmControllable particle size
0–500 mL/minFlow rate range
±1%Pump flow accuracy
10 MPaMax. working pressure
Products

Three Platforms Covering the Entire Nano-Formulation Workflow

High-throughput screening, benchtop development and pilot scale-up share the same microfluidic mixing principle and chip family — formulation parameters optimized in the lab transfer seamlessly to production scale.

NP-HT.S High-Throughput Nanoparticle Synthesis System
High-Throughput · Ultramicro Screening

NP-HT.S High-Throughput NP Synthesis System

High-Throughput Nanoparticle Synthesis System

An ultramicro-volume screening platform with 8-channel parallel synthesis and 20–30 s per run: as little as 60 μL per channel, tubing-free zero-dead-volume chip, compact enough for biosafety cabinets.

  • 8 channels in parallel — thousands of formulations per day
  • 60–300 μL per channel, up to ~95% reagent savings
  • Particle size 40–200 nm, PDI ≤ 0.2
  • EO-sterilized chip, automation-ready
NP-HT.S details
NP-S2 Smart NP Generator
Benchtop · R&D Preparation

NP-S2 Smart NP Generator

Smart NP Generator S2

An intelligent benchtop synthesis platform with full touch-screen control of TFR/FRR and every process parameter — one-step formation, controlled particle size, high reproducibility.

  • Particle size 30–200 nm, FRR from 10:1 to 1:30
  • Sample volume 0.4–40 mL, standard 1–20 mL Luer syringes
  • Standard COC chip; 316L stainless / glass optional
  • Touch control; optional PC software + audit trail
NP-S2 details
NP-M1 Pilot-Scale Nanoparticle Generator
Pilot · Scale-Up Production

NP-M1 Pilot-Scale NP Generator

Nanoparticle Generator for Pilot Scale

A modular pilot-scale platform for LNPs, polymeric nanoparticles and emulsions, with optional heating, in-line dilution and automatic waste switching, compliant with 21 CFR Part 11.

  • Dual high-pressure + ambient channels, up to 500 mL/min
  • Non-contact mass flow meters with real-time feedback
  • Liquid path heatable to 80 °C; 316L tubing for cGMP
  • Three-tier access, e-signature, audit trail
NP-M1 details
Applications

Applications

One platform family serving nucleic acid drugs, vaccines, delivery systems and advanced formulations across many nanoparticle preparation scenarios.

mRNA Vaccines & LNP Drugs

LNP formulation screening, process development and pilot scale-up for mRNA vaccines and siRNA therapeutics.

Liposome Formulations

Consistent preparation of conventional and novel lipid carriers with narrow size distribution and low batch-to-batch variability.

Polymeric Nanoparticles (PLGA)

Nanoprecipitation of biodegradable polymers such as PLGA and PCL for sustained-release formulations.

Exosome Drug Loading

Drug loading and post-processing of exosomes and extracellular vesicles as natural nanocarriers.

Nucleic Acid Delivery (DNA / RNA / RNP)

Payloads from DNA and RNA to RNP, peptides and small molecules — full coverage of gene-therapy payloads.

Cosmetic Nanoemulsions

Continuous preparation of nanoemulsions and lipid carriers for cosmetic active ingredients.

Technology

Microfluidic Mixing Technology

Nanoparticle self-assembly driven by precisely controlled hydrodynamics: total flow rate (TFR) governs particle size and mixing efficiency, while flow rate ratio (FRR) governs composition and nucleation — digital parameters, repeatable and scalable results.

1

Lipid / Organic Phase

Lipids or polymers dissolved in ethanol or other organic solvents

2

Precise Metering

Fully digital TFR and FRR setting with ±1–2% accuracy

3

On-Chip Mixing

Impinging jet / vortex / SAR mixing architectures

4

Self-Assembly

Supersaturation-driven assembly into uniform nanoparticles

5

Post-Processing

In-line dilution, dialysis purification, concentration, filling

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